This chapter will introduce the reader to the scientific approach that is required to both comprehend and safely practice forensic podiatry. A thorough explanation of what is needed for evidential purposes, a discussion of class and individual characteristics, and a short explanation of the Bayesian approach to forming conclusions in the consideration of pedal evidence is provided. A discussion of evidence handling and the methodology that would be utilized which parallels that of other disciplines is given (including the ACE-V(R) – Analysis, Comparison, Evaluation, Verification, Reporting approach). Some basic information relative to the requirements necessary to be a credible expert witness in this field is also presented.